
Who would he play? “The Joker,” he laughed, or maybe “the Riddler.”
Personally, I think the Riddler would be a better choice for NPH. Just imagine, the guy would be an awesome Ed Nigma!

Buffy VS The Beatles? Firefly VS Demi Lovato? Angel VS Star Wars?
Yep. It’s the Ultimate Fan Battle! Cast a vote for our Whedonverse favorites NOW!
Castle, Bones and How I met Your Mother, all starring some of our Whedon alumni, are also in the battle.
Neil Patrick Harris talks DR. HORRIBLE II, How I Met Your Mother, Oscars, M&Ms and more!

One more question: Do you think a Dr. Horrible sequel will ever happen?
I do. I know Joss (Whedon) is excited about it, Nathan (Fillion) would love to do one, Felicia (Day) as well. And I would certainly be on board. I just have this sneaking feeling in my gut that they would make a Dr. Horrible feature film and then cast Andrew Garfield as Dr. Horrible.
No!
We’ll see what happens. (Laughs)
READ THE COMPLETE INTERVIEW HERE.